Our group successfully published a paper on STAT5 signaling in lipid metabolism in the journal “Molecular Metabolism”.
Doris Kaltenecker and Katrin Spirk were working together on this project and investigated the function of STAT5 in brown adipose tissue thermogenesis, as well as its role in the brown remodelling of white adipose tissue. They demonstrate in their work the importance of STAT5 for the functionality and the β-adrenergic responsiveness of thermogenic adipose tissue.
STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue.
Kaltenecker D, Spirk K, Ruge F, Grebien F, Herling M, Rupprecht A, Kenner L, Pohl EE, Mueller KM, Moriggl R. Mol Metab. 2020 May 27:101026. doi: 10.1016/j.molmet. 2020. 101026. Online ahead of print. PMID: 32473405
Congratulations Doris and Katrin!
The Moriggl Lab 